Code: F7ADIBMC Biophysical Modeling in Cardiology
Lecturer: Dr. Peter van Dam PhD Weekly load: 20P+8C Completion: EX
Department: 17110 Credits:  Semester: W,S
Description:
The course provides with basic and applied information on the genesis of the ECG, VCG, electric volume conduction, forward and inverse problem in electrocardiology eventually also on mechanical heart modeling (CircAdapt).
Contents:
1. Electrical functioning of the heart: Clinical Aspects
2. Electrical functioning of the heart: electro-physiology
3. The ECG: signal analysis
4. Electrical functioning of the heart: Modeling I (source models)
5. Electrical functioning of the heart: Modeling II (volume conduction)
6. Electrical functioning of the heart: Modeling III (specific disease modeling, ACM)
7. ECGsim
8. The inverse problem in electrocardiography I
9. The inverse problem in electrocardiography II
10. SciRun, solving an inverse problem.
Seminar contents:
1. Simulation of the ECG.
2. Inverse problem solving. Datasets will be available to solve the inverse problem suing SCirun. Base on these work an end report needs to be created.
Recommended literature:
Required:
[1] Barr R.C., van Oosterom A. (2010) Genesis of the Electrocardiogram. In: Macfarlane P.W., van Oosterom A., Pahlm O., Kligfield P., Janse M., Camm J. (eds) Comprehensive Electrocardiology. Springer, London
[2] T. F. Oostendorp and A. van Oosterom, "Source parameter estimation in inhomogeneous volume conductors of arbitrary shape," in IEEE Transactions on Biomedical Engineering, vol. 36, no. 3, pp. 382-391, March 1989.
Recommended:
[1] A. van Oosterom. T.F. Oostendorp. Electric Volume Conduction in Bio-medicine. Laboratory of Medical Physics and Biophysics Catholic University Nijmegen, Nijmegen. The Netherlands. April 2015.

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