Code: F7ABBFCH Physical Chemistry
Lecturer: prof. Ing. Karel Roubík Ph.D. Weekly load: 2P+1C+1L Completion: A, EX
Department: 17110 Credits: 4 Semester: W
Description:
Physical and chemical properties of substances. Basic calculations. Principles and behavior of systems of
gases and liquids. Chemical bonds. Properties of solvents. Electrolytes. Dissociation of substances.
Phase equilibria, multiface systems. Behavior and properties of vapors, evaporation. Electrochemical
potential, electrodes. Electrodes of first and second kind. Referent and indication electrodes, electrodes
for EKG, EEG, EMG etc. Redox potential. Inert electrodes. Membranes - types, properties and
applications. Osmotic pressure. Ion selective electrodes. Acidity and basicity of solutions, pH. pH
measurement. Stability of materials, corrosion. Passivation and self-passivation. Electrolysis and
conductivity of solutions and its measurements. Polarography. Further methods of analysis of gases and
solutions in BME (Biomedical Engineering.) Optical absorption. Spectrophotometry. Fluorescence and
phosphorescence. Sensors for measuring of pH, pO2, pCO2, and SaO2 working on the basis of fibre optic
cables and absorption or fluorescence. Advanced analytical devices. Mass spectroscopy, nuclear
magnetic resonance, flame spectroscopy. Thermodynamics of reaction systems, basic calculations.
Contents:
Syllabus of lectures:
1. Objectives of the subject. Basic principles of physical chemistry. Physical and chemical properties of compounds.
2. Principles and properties of gaseous systems. Properties and structure, calculations of composition of gas mixtures, state equations and state processes.
3. Structure and properties of liquids. Solutions. Dissolving, solubility. Properties of solvents.. Viscosity, surface tension.
4. Dispersion systems, colloids - classification, ultrafiltration, dialysis, optical properties.
5. Phase equilibria, multicomponent systems. Behavior and properties of vapor, evaporation, saturated and overheated vapor. Principles of humidifiers and vaporizers of anesthetic substances, further applications in Biomedical engineering.
6. Dissociation of substances. Acidity and basicity of solutions. pH.
7. Elecrotolytes. Electrolysis. Conductivity of solutions and its measurement. Polarography.
8. Electrochemical potential, electrodes. Nernst equation. Electrodes of first kind. Electrochemical halfcell and cell, concentration cell. Application in BME (Biomedical engineering.)
9. Electrodes of second kind. Solubility product. Referent and indication electrodes of second type, electrodes for EKG, EEG, EMG etc.
10. Redox potential. Oxidation strength of media. Inert electrodes. Calculation of redox potential. Application in BME.
11. Membranes - types, properties and application. Osmotic pressure. Ion selective electrodes. pH measurement.
12. Optical properties of molecules. Fluorescence and phosphorescence. Optical absorption. Spectrophotometry. Application in BME.
13. Sensors for measurement of pH,po2, pco2 and so2, working on the basis of fibre optic cables and absorption and fluoresce. Application in BME
14. Stability of materials, corrosion. Anodic curves of metals, passivation and self-passivation. Oxidation properties of different media and their influence on the rate of corrosion.
Seminar contents:
1. Chemical laboratory - equipment and usage. Safety in the laboratory, safety procedures. Calculations of concentration and pH.
2. Calculations of pH.
3 .Calculations of electrode potentials, voltage of cells, conductivity.
4. .Calculations of electrode potentials, voltage of cells, conductivity.
5. Calculations of solubility, electrolysis.
6. Test I.
7. Measurement of electrode potential.
8. Measurement of Redox potential.
9. Measurement of pH.
10. Measurements of conductivity.
11. Measurement of ion selective electrode.
12. Measurements of electrode potential.
13. Test II.
14. Assessment
Recommended literature:
[1] Atkins, P., Paula, J.: Atkins' Physical Chemistry. (Eighth Edition). Oxford University Press, Oxford, 2006.
[2] Raff, M. L.: Principles of Physical Chemistry. (Paarts 1 and 2). Prentice Hall, Upper Saddle River, 2001.

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