Code: 17AMPNCM Nanoparticles and Nanomaterials - Properties and Biomedical Applications
Lecturer: prof. Ing. Miroslav Jelínek DrSc. Weekly load: 2+2 Assessment: Z,ZK
Department: 17101 Credits: 4 Semester: W
Description:
Methods for determination of properties (nanocrystalline, grain size, size, shape, surface, chemical composition) of nanoparticles, nanofibres, and nanocomposites. Attention will be given to basic principles of microscopic techniques.
Especially to:
1) optical and confocal microscope, atomic force microscope, scanning tunneling microscope, scanning near-field microscope, etc.
2) crystalline structure related methods based on X-Ray diffraction(XRD) diffraction of high-energetic (RHEED) and low-energetic (LEED) electrons,
3) determination of bonds (including the sp2/sp3 ratio of carbon bonds) by spectrometric methods: Raman scattering, Fourier transformed infrared spectrometry, X-ray photo-electron spectroscopy (XPS),
4) method for elemental analysis: Rutherford backscattering (RBS), Secondary Ion Mass Spectroscopy (SIMS), Glow Discharge Optical Emission Spectroscopy (GDOES), spectroscopy of secondary electrons (EDS, WDS), Particle Induced X-Ray Emission (PIXE),
5) optical properties (elipsometry, transmisivity),
6) mechanical and surface properties (microhadness, adhesion, wettability, z-potential), electric, biocompatible, magnetic properties.

Students will take part in laboratory exercise on devices used in regularly scientific work. Such as: optical microscope, atomic force microscope, scratch tester, nano-indentation, contact angle measurement device, FTIR spectrometer.
Contents:
1 Basic characterization methods - summary, division. Basic principle of microscope methods Optical microscope.
2 Confocal and fluorescent microscope
3 Surface probe microscopy, atomic force microscopy, scanning tunnelling microscope, scanning near-field microscope, etc.)
4 Atomic force microscopy (J. Remsa - Albertov)
5 Method for characterization of biocompatible materials, nanocomposites a multilayers. Requirements on characterization of biomaterials, and principle of method selection.
6 Deans day.
7 Methods for crystalline structure determination (XRD, RHEED), grain size distribution. Test 1.
8 Methods for bonds measurement (Raman scattering, FTIR, XPS, methods for the sp2/sp3 ratio determination for carbon).
9 State holiday.
10 FTIR and her applications for nanotechnology. Raman spectroscopy. J. Remsa - Albertov
11 Chemical composition methods (RBS, PIXE, SIMS, GDOES, EDS, WDX).
12 Optical properties methods (ellipsometry, transmissivity).
13 Methods for mechanical and surface properties (micro-hardness, adhesion, wettability, zeta-potential).
14 Final test (Test č. 2)
Recommended literature:
Chrisey, D.B., Hubler, D.K.: Pulsed Laser Deposition of Thin Films. John Wiley and Sons, Inc., 1994
Prasad, P.N.: Nanophotonics. Wiley Interscience 2004
Miller, J.C., Haglund, R.: Laser ablation and desorption, Vol. 30, Experimental Methods in the Physical Sciences, Academic press, 1998
Cahn Frs, R.V.: Concise Encyclopedia of Materials Characterization, Elsevier, 2005
Brundle, C.R., Evans, C.A., Wilson, S., Fitzpatrick, L.E.: Encyclopedia of materials characterization, Butterworth- Heinemann , 1992
Cullity, B.D.: Elements of X- ray Diffraction, Adison- Wesley, Menlo Park, CA, 1978
Klug, H.P., Alexander, L.E.: X - ray Diffraction Procedures, Wiley, New York 1974
Prasad, P.N.: Nanophotonics. Wiley Interscience 2004
Keywords:
thin films, polymeric nanocomposites, nanostructures and nanoelectronics, biosensors, nanowires, nanomedicine