Mixtures of compounds. Vapour and vaporisation. Electrodes. Electrochemical potential, electrodes. Referent and measuring electrodes, ECG, EEG and EMG electrodes. Redox potential. Inert electrodes. Membranes. Osmotic pressure. Ion-sensitive electrodes. Acidity. Measurement of pH, pO2, pCO2. Electrolysis and its application. Corrosion and protection of implants. Other amalytical methods based on principles of physical chemistry.
1. Objectives of the subject. Basic principles of physical chemistry. Physical and chemical properties of compounds. Basic calculations.
2. Mixtures of compounds-gases.
3. Mixtures of compounds-solid and liquid compounds.
4. Evaporation, saturated vapour. Humidifiers and vaporizers of anaesthetic compounds.
5. Electrochemical potential, electrodes. Nernst equation. Electrodes of the first type. Electrochemical cell and half-cell. Application in biomedical engineering.
6. Electrodes of the second type. Solubility product. Reference electrodes. ECG, EEG and EMG electrodes.
7. Redox potential. Inert electrodes. Calculation of redox potential. Application in BME.
8. Membranes-types, properties and application. Osmotic pressure. Ion-sensitive electrodes. Acidity of solutions, pH. Measurement of pH.
9. Stability of materials and corrosion. Anodic reactions. Corrosive speed.
10. Electrolysis, conductivity of solutions and its measurement. Other methods for analysis of solutions and gases. Applications in BME.
11. Optical absorption. Spectrophotometry, etc. Application in BME.
12. Fluorescence a phosphorescence. Sensors for pH, pO2, pCO2 and SO2 measurement based on optical principles.
13. Advanced analytical methods and equipment. Mass spectroscopy, nuclear magnetic resonance, atomic absorption spectrophotometry, etc.
14. Thermodynamics-basic principles and calculations.
 Atkins, P., Paula, J.: Atkins' Physical Chemistry. (Eighth Edition). Oxford University Press, Oxford, 2006.
 Raff, M. L.: Principles of Physical Chemistry. (Paarts 1 and 2). Prentice Hall, Upper Saddle River, 2001.